• Nanion Technologies: Smart Tools for Ion Channel Research

    Nanion Technologies: Smart Tools for Ion Channel Research

  • CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

    CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

  • SURFE²R 96SE: Label-free HTS Transporter Screening

    SURFE²R 96SE: Label-free HTS Transporter Screening

  • Bilayer recordings: Orbit product family

    Bilayer recordings: Orbit product family

  • SURFE²R Webinar: January 30

    SURFE²R Webinar: January 30

    Read more

Our Product Portfolio

SyncroPatch 384/768PE

SyncroPatch 384/768PE

Patchliner

Patchliner

Port-a-Patch

Port-a-Patch

CardioExcyte 96

CardioExcyte 96

SURFE2R 96SE

SURFE2R 96SE

SURFE2R N1

SURFE2R N1

Orbit 16

Orbit 16

Orbit Mini

Orbit Mini

Vesicle Prep Pro

Vesicle Prep Pro

Newsblog Entry (10.01.2018): New SyncroPatch 768PE paper published in PNAS

Title: "Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors"

Scientists at Genentech and Xenon have worked together to propose a new mechanistic approach using patch clamp electrophysiology to identify NaV1.7 selective compounds. By using a pore mutant of NaV1.7 and using the SyncroPatch 768PE, the scientists were able to identify NaV1.7 selective compounds acting via other mechanisms than pore blocking.

 

Download the full paper here.

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Nanion Technologies GmbH

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