• CardioExcyte 96

    Combined impedance and MEA-like recordings
  • CardioExcyte 96

    For cardiac safety screening
  • CardioExcyte 96

    Next generation label-free cell analysis
  • CardioExcyte 96

    Intuitive data analysis & arrhythmia detection
  • CardioExcyte 96

    Transparent plates available for imaging

Cardiomyocytes - Dofetilide and its concentration dependent effect on Cor.4U cells

Icon CE   Dofetilide Cor4uCardioExcyte data and applications:
Cells were kindly provided by Axiogenesis.

Dofetilide is a class III antiarrhythmic agent, which has pro-arrhythmic potential.
It selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr). Impedance and EFP recordings reveal a concentration dependent effect on e.g. amplitude and FPD as expected.

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Nanion Technologies GmbH

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D-80339 Munich - Germany