Nanion Technologies

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Data and Applications


Hemolysin block by mono- and polyPEGs

2011_HL_Hist

Current traces and histograms derived from recordings of αHL pores blocked by monoPEG-28 and polyPEG-1500 on an Ionera MECA chip (AxoPatch 200B, filter freq: 20kHz, digitized at 200 kHz).

Click here to download the full paper. (Am. Chem. Soc Nano, 5(10), 8080-8088, 2011)

Data courtesy of Dr. Gerhard Baaken et.al, University of Freiburg / Ionera.

Parallel alamethicin recordings

Alamethicin_Ionera

The data image shows parallel recordings from reconstituted alamethicin channels (University of Freiburg/ Ionera1). In a recent paper, the MECA recording technology was successfully used for the reconstitution of α-haemolysin pores in bilayers and detection of polymers translocating over the α-haemolysin pore.

Data courtesy of Dr. Gerhard Baaken, University of Freiburg / Ionera.

Parallel recordings of monoPEG-28 block of hemolysin

2011_Hemolysin

Event-averaged histograms (black) and overlaid current traces (blue) of parallel and simultaneous recordings on a MECA chip of monoPEG-28-mediated blockages of hemolysin nanopore(s). The current traces were recorded with a multichannel amplifier (Tecella Jet 16). Histograms were derived from the mean current levels of at least 2000 visits of blocked stated per cavity (20 kHz sample frequency).
Click here to download the full paper. (Am. Chem. Soc Nano, 5(10), 8080-8088, 2011)

Data courtesy of Dr. Gerhard Baaken et. al., University of Freiburg / Ionera.